Rampiril Side Effects

What Is Ramipril?

ramipril side effectsRamipril is a drug that used to decrease and regulate blood pressure. It is an angiotensin converting (ACE) reductor and its main role is to inhibit the emission of angiotensin II. The role of angiotensin II is to narrow the arteries and blood vessels. The reduction of the angiotensin II leads to the relaxation of the small blood vessels muscle. Due to the realxation of the arteriole muscles, the diameter of the vessels is increased, leading to a lower blood pressure.

Ramipril is usually prescribed mainly for congestive heart failure and hypertension, but it’s also prescribed to patients that have suffered a heart attack, or to patients clearly susceptible of heart failure. It’s also recommended to prevent strokes and heart attacks, microalbuminuria and nodular diabetic glomerulosclerosis. Lastly, ramipril is recommended in case of revascularization. In any case, to avoid any dangerous ramipril side effects, it’s best for this drug not to be take in conjunction with other drugs, before asking a physician.


Ramipril should be administered one per day, at the same hour. However, in some cases a different dosage may be prescribed, so it’s for the best to follow your doctor’s advice in case he or she has prescribed you this drug. The absorption of ramipril isn’t favored if it’s taken before or after meals, or with a meal. However, it’s important for the tablets to be swallowed whole, with water. In case you have forgotten to take a dose, do not take two the next day.

Ramipril Side Effects

Just like most of the drugs out there, ramipril has its share of side effects. Some of the low-impact ramipril side effects are: light-headedness and dizziness due to the effect of decreased blood pressure, nausea and/or vomiting, gastrointestinal problems like stomach pain or diarrhea. Fatigue may be experienced at the beginning of the treatment with this drug.

Patients on medications for diabetes may experience low blood sugar which usually leads to excessive sweating or shivers.

One of the most common, and most discomforting mild ramipril side effects is dry cough. Most patients on medication with angiotensin convertin enzyme inhibitors like ramipril or quinapril have this side effect. The only way to stop this non-expectorant cough is to cease the treatment with ramipril. Very often, the dry cough is accompanied by sore throat and dry mouth.

The last of the Ramipril side effects that can be considered mild is excessive or insufficient urination.

There are of course, more severe Ramipril side effects. These are: fainting, dark urine, infection symptoms (e.g. fever), impotence and neutropenia.

Now, the dark coloration of the urine can be a sign of kidney or liver disorder or failure. In a case like this, immediate medical attention is necessary.

Also, neutropenia or the low level of white blood cells, is equivalent with a weak immune system. The white blood cells are the first defensive mechanism of the human body against infections with various pathogens. Their main role is to consume the bacteria found in the blood.

Of course, there’s a chance for any patient to develop or have an allergic reaction to ramipril. Although cases of allergic reactions to this drug were rarely reported, they usually include skin rashes, skin itchiness, facial edema (swelling of the face), swelling of the throat, mouth or tongue, and anaphylaxis. In case of any allergic reaction to this drug quick medical help is required.

Ramipril Contraindications

Ramipril can have a serious impact to the liver and kidneys. Therefore, it’s not recommended to patients with severe kidney problems such as renovascular disease, renal artery stenosis or patients undergoing dialysis. Also, extreme cases of liver failure have been reported on patients under medication with ramipril. Therefore, in case of liver problems or history with a liver disease, this ACE inhibitor isn’t recommended as it may increase the risk of fatal liver failure.

Ramipril isn’t indicated to patients with collagen vascular diseases, like scleroderma or systemic lupus erythematosus. Hypotension should also be on the list of ramipril contraindications.

In case you must follow a diet with salt restrictions, or have to use potassium salt substitutes, it’s best to notify your doctor if they are to prescribe you this drug. Also, ramipril may interfere with various herbal teas or supplementary naturist treatments. So, in general, if you have a blood pressure problem or congestive heart failure, it’s best to report to your doctor exactly what other drugs or alternative medicine you take, so that in case they will prescribe this drug to you, you will be able to avoid any severe ramipril side effects.

Lastly, ramipril is not recommended during pregnancy or breast-feeding.

Words of Advice

Since ramipril is a drug prescribed usually for non-curable, but manageable conditions, it’s best to not skip any appointments with your doctor, so that they can monitor your condition better.

Ramipril treatment is usually long term or it may be necessary for the whole life of the patient. However it’s usually prescribed to patinets over their 50 years old. Since some of the most usual ramipril side effects are nausea or dizziness it’s very important not to take your dose before operating heavy machinery, taking any dangerous job, or before driving. Alcohol may enhance the dizziness produced by this drug, so it’s best not to consume alcohol at all, or at least for a few hours after, or before you have taken your pill.

In case of a headache, not all the pain killers are recommended to take in conjunction with ramipril, so you should ask your doctor or the pharmacist to recommend you a few, to be sure you won’t experience any adverse effects. The opinion of the pharmacist may be very useful in case you’re buying any other over-the-counter medicines.

As I mentioned above, diarrhea, vomiting or gastrointestinal problems are side effects that may occur due to the intake of ramipril. To reduce the risk of these side effects it’s best to eat small quantities of food, but more often. Also, keep away from spicy foods.