Bendroflumethiazide and the Side Effects

What Is Bendroflumethiazide

bendroflumethiazide side effectsBendroflumethiazide is a thiazide diuretic drug, also known as a water tablet, or water pill. In general, all diuretics are drugs that inudce a high urination rate, eliminating the water from the body, to control and manage certain conditions or diseases.

Bendroflumethiazide is used specially to treat hypertension. Also, it’s used to treat various types of edema, and to diminish the risk of heart failure and stroke. Its way of action is to reduce the absorption process of sodium in the body, which results in a loss of water.

Thiazide diuretics are the cheapest and most widespread drugs for lowering blood pressure available, and this does not exclude bendroflumethiazide.

Bendroflumethiazide Side Effects

Due to the fact that this drug blocks the absorption of sodium, some of the bendroflumethiazide side effects include various mineral disbalances in the body. These are:

  • Hyponatremia or an electrolyte disbalance in which case the sodium concentration in the blood is lower than normal. Hyponatremia has symptoms as nausea, vomiting, fatigue, loss of apetite, muscle pain, muscle weakness or even coma;
  • Hypokalemia or low blood level of potassium is also one of the bendroflumethiazide side effects, or in general, one of the most common adverse effects caused by the intake of thiazide diuretics. This condition comes with symptoms like mild elevation of the blood pressure, cardiac arrhithmias, muscle weakness and cramps, constipation, or even flaccid paralysis;
  • Hypercalcaemia or an increased blood level of calcium. Although this disbalance can be asymptomatic, patients that may experience the following symptoms: kidney of biliary stones, gastrointestinal problems, bone pain, insomnia, anxiety, depression.

Since most diuretics augment urination, hyperuricemia (high blood level of uric acids) may occur. This may lead to gout (acute inflammatory arthritis – or, in other words, swollen, painful joints). However, gout is also induced by a meat-based diet. Therefore, while under medication with bendroflumethiazide, a specific diet should be recommended.

Another one of the bendroflumethiazide side effects is erectile dysfunction. In general, especially in men with hypertension, erectile dysfunction may occur after treatment with antihypertensive drugs. For men with hypertension the maintenance of a higher blood pressure is necessary to obtain a normal erection. Also, bendroflumethiazide can cause postural hypotension, also known as head rush. So, if you’re on medication with this drug, it’s not recommended to get up or lay down very fast.

Bendroflumethiazide can inhibit lactation, and it’s not recommended to breastfeeding mothers, especially in the first month after pregnancy. However, it studies haven’t shown any significant bendroflumethiazide side effects on infants breastfed by mothers under treatment with this drug.

And the last of the common bendroflumethiazide side effects is an elevation of the sugar blood level. That’s why this drug is contraindicated to patients with diabetes or hyperglycemia.

There are also a few rare bendroflumethiazide side effects. These are:

Pancreatitis – the inflammation of the pancreas. This usually occurs when some of the pancreatic enzymes are activated inside the pancreas and not in the small intestine. It’s known that some diuretics may cause this condition in certain patients.

Thrombocytopenia – an increased level of platelets in the blood.

Agranulocytosis – low blood level of neutrophils (white blood cells), which basically results in a depressed immune system.

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